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Decreasing waist circumference with stable or increasing limb measurements suggests favorable fat loss with lean mass preservation

Zhu B, Gong N, Fan H, Peng CS, Ding XJ, Jiang Y et al (2014) Lamiophlomis Rotata, an orally available tibetan herbal painkiller, specifically reduces pain hypersensitivity states through the activation of spinal glucagon-like peptide-1 receptors

(2022) Efficacy of once-weekly tirzepatide versus once-daily insulin degludec on glycaemic control measured by continuous glucose monitoring in adults with type 2 diabetes (SURPASS-3 CGM): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial

These mechanisms are central to restoring function in type 2 diabetes as in that condition glucose does not stimulate adequate Ca 2+ influx