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There remains an unmet need for weight-management medications that can facilitate nonsurgical, sustained weight reduction and reduce pain in persons with obesity-related knee osteoarthritis, they added

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Orforglipron eliminates these considerations entirely, allowing patients to take their tablet at any time of day, with or without food, with whatever beverage they prefer, and in any sequence relative to other medications

Ozempic is primarily used to treat type 2 diabetes, but it has also been found to be effective in promoting weight loss