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Compounded GLP-1 medications are not FDA-approved finished drug products - prescription eligibility requires licensed clinician review and is never guaranteed

But doctors warned that such products could make people ill or cause serious health complications

A recent study demonstrated that NLRP3/caspase-1/GSDMD-mediated pyroptosis in fibroblasts is relatively limited compared with that in macrophages, which express high levels of NLRP3, caspase-1 p20 and GSDMD-NT under LPS plus ATP stress, a strong NLRP3 inflammasome activator and pyroptotic trigger

Blunted glucose-stimulated insulin secretion , compromising glycaemic control

Holst et al ., 1987