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Why Gas and Bloating Usually Get Better Over Time Most patients report that gas and bloating peak in week 23 and gradually improve by week 68 as the body adapts to slower stomach emptying

particularly nausea and vomiting to support treatment continuity

There are two types: gastric inhibitory polypeptide (GIP), secreted from K cells present in the upper intestine, and glucagon-like peptide-1 (GLP-1), secreted from L cells present in the lower intestine and large intestine 25

It was developed by Eli Lilly as part of a broader effort to improve on first- and second-generation incretin-based therapies

doi: 10.1016/j.jri.2011.09.003 [DOI] [PubMed] [Google Scholar] 37.du Sert N P, Hurst V, Ahluwalia A, et al