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Tirzepatide is a novel glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for two distinct indications: treatment of type 2 diabetes mellitus (Mounjaro) and chronic weight management (Zepbound) in adults with BMI 30 kg/m or 27 kg/m with at least one weight-related comorbidity

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Retatrutides combined pathway appears to reduce: fasting blood sugar post-meal spikes insulin load insulin resistance Liver-Fat Reduction Glucagon activation can significantly reduce liver fat, making retatrutide a promising candidate for NAFLD and metabolic syndrome treatment

Collagen: While data is mixed, collagen peptides may support skin elasticity during weight loss