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However, there are other data that would challenge the simple explanation that the reduction in feeding and body weight resulting from CNS GLP1R agonism is simply explained by inducing an aversive visceral state

Pfizer provides update on oral GLP-1 receptor agonist danuglipron

doi: 10.1111/obr.13709

Rezaie, G.A

To properly discuss these concerns, its important to first understand how GLP-1 drugs actually work