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In addition, in January 2025, Medicare announced it will include semaglutide products (Ozempic, Rybelsus, and Wegovy) in its second round of drug price negotiations, treating all three brands as a single drug due to their shared active ingredient.28 With negotiated prices set to take effect in 2027, this could significantly reduce costs for Medicare beneficiaries

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While this body of evidence is highly encouraging, it is important to note that these findings are derived from studies with considerable methodological heterogeneity, a limitation that will be addressed in the Discussion

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