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While these drugs offer significant preoperative weight loss benefits, their impact on surgical outcomes, tissue healing, and perioperative complications remains unclear

In this paper, the authors describe the energy state-dependent regulation of the PVNGLP-1R to DVC circuit, resulting in altered food intake and metabolic health, mediated by GLP-1 receptor signalling.

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Developed images revealed clear excess adiposity and high health-risk (BRI) at baseline with marked improvements, although not to within the healthy BMI (<25kg/m2) and BRI ranges at 72 weeks, observations not evident in the published report

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