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Eli Lilly announced Phase 3 ATTAIN-1 trial results for orforglipron, an oral GLP-1 receptor agonist, showing significant weight loss in adults with obesity or overweight without diabetes

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The WHO guidelines call for urgent action on manufacturing, affordability, and system readiness, recommending strategies such as pooled procurement, tiered pricing, and voluntary licensing to expand global access [51]

In its preclinical pitch deck, ASC35 outperformed once-weekly tirzepatide by about 71% in diet-induced obese mice and showed a half-life roughly six times longer than tirzepatide in non-human primates