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In addition to decreasing the fluidity of the platelet membrane and promoting platelet aggregation, coagulation factors and PAI-1 (plasminogen activator inhibitor-1) will also increase under the condition of hyperglycemia, breaking the balance of coagulation and fibrinolysis and promoting thrombosis

Materials and methods Study design We performed a retrospective cohort analysis using de-identified patient data through TriNetX Global Collaborative Network, providing access to 200 million anonymized electronic health records and over 140 healthcare organizations

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Theres also emerging evidence of anti-inflammatory properties and improved blood sugar regulation, which can support recovery and metabolic efficiency during prolonged exertion

N Engl J Med 372(23):21972206 Hernandez AF, Green JB, Janmohamed S, DAgostino RB Sr, Granger CB, Jones NP, Harmony Outcomes committees and investigators et al (2018) Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovasculardisease (Harmony outcomes): a double-blind, randomised placebo-controlled trial