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Overdosing may cause severe gastrointestinal side effects such as severe nausea, vomiting, hypoglycemia, and hospitalization due to the long half-life of semaglutide

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In a Chinese T2DM cohort treated with GLP-1R agonists, carriers of the GLP1R rs3765467 GG genotype experienced significantly greater HbA1c reduction compared to AA/AG genotypes [87]

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