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Long-Term Medication Users Medications such as metformin (used for diabetes) and proton pump inhibitors (used for acid reflux) can interfere with B12 absorption when taken long term, making supplementation necessary

Thirty-two mature rats were divided into four groups and administered varying doses of the seaweed extract over a month (50, 100, and 150 mg/cm 3 of the extract/0.5 B.wt)

Theres just one small problem: not a single randomized controlled trial has ever been completed in humans

Autonomic nerves, which control both voluntary and involuntary bodily functions such as blood pressure, may also be affected

The body stores Vitamin B12 readily, so maintenance may not be necessary or requested by patients for several months at a time