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In addition, ROS cause protein and DNA damage, as well as changes in cell membrane structure through LPO, affecting signaling pathways and neuronal electrophysiological properties that lead to increased neuronal excitability in the early stages of neurodegenerative diseases

ZhangL.et al.2000Hepatocyte growth factor protects cultured rat cerebellar granule neurons from apoptosis via the phosphatidylinositol-3 kinase/Akt pathway, 99
doi: 10.1016/j.plaphy.2025.109633 23 ChengH.ShiX.LiL

A., Su, S

Researches show that aging, chronic degenerative diseases like Parkinsons, Alzheimers disease are strongly associated with a reduced level of glutathione in brain cells
