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Neurochem Res 14:377389 Kauppinen RA, Sihra TS, Nicholls DG (1987) Aminooxyacetic acid inhibits the malate-aspartate shuttle in isolated nerve terminals and prevents the mitochondria from utilizing glycolytic substrates

Witting M

Using native chemical ligation in solution or on resin coupled with oxidative folding the protein was successfully prepared

Furthermore, comparing Prdx Km for H 2 O 2 with that of GPx and catalase exceeding even the millimolar range [180] suggests that the role of Prdx is rather as a sensor of H 2 O 2 [178] than oxidative stress condition reversal

Glutathione (L--glutamyl-L-cysteinyl-glycine) is the most abundant non-protein thiol in mammalian cells, present in millimolar concentrations throughout the body with particularly high concentrations in the liver, kidneys, and immune tissues