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Notably, only a very short exposure of cells with low erastin concentrations was sufficient to cause a strong and persistent inhibition of system xc, causing glutathione depletion
Study Objectives: The pathophysiology of restless legs syndrome (RLS) may be related to abnormalities in central dopamine pathways
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The presenilins promote the expression of GPX4, the selenoprotein checkpoint enzyme that blocks ferroptosis by quenching the membrane propagation of lethal hydroperoxyl radicals
