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Description
A temporary trial is usually performed before permanent implantation to confirm meaningful relief

TNF- expression was found to be elevated in the IVD and peripheral serum in patients with degenerated IVDs

J Pharmacol Sci 2006

Important considerations when utilizing the cuprizone model for preclinical therapeutic efficacy studies as part of drug development studies include determining the appropriate time window for both the intervention and the endpoint readouts

These create stiff, painful areas that won't heal normally