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Description
Preservative-free options like sterile water or SWFI are generally reserved for situations where the entire reconstituted volume will be used at once, or where a particular protocol specifically calls for a preservative-free diluent

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A cross-sectional, controlled study on Metformin that included both diabetic and non-diabetes patients showed no that irrespective of Metformin use, no significant difference in the serum levels of vitamin B12 was observed, both in patients with and without diabetes (5)

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