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The inability of affected cell to clear nonfunctionally associated PD-specific Syn variants with endogenous proteins has a detrimental effect on postmitotic neurons, a phenomenon previously reported in prion-infected cells 82
Carboplatin is relatively well tolerated clinically, causing less nausea, neurotoxicity, ototoxicity, and nephrotoxicity than cisplatin

Mid-Tier Treatments: NAD+ nasal spray ($125/month), sermorelin injections ($99/month), and compounded semaglutide ($139/month) sit in the moderate range

doi: 10.1016/J.PSYCHRES.2014.04.005
