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The risks fall into three buckets Common, mild, self-limiting Bruising or soreness at the catheter site Cool sensation along the arm during the drip Warm flush or metallic taste, especially with magnesium or B-complex Mild lightheadedness if the drip runs too fast Uncommon Phlebitis, or vein irritation, especially with stronger or more concentrated formulas Infiltration (fluid leaking under the skin if the catheter shifts) Allergic reactions to specific ingredients, particularly thiamine and B-complex Rare but serious Infection at the IV site Fluid overload in patients with heart, kidney, or liver disease Electrolyte disturbances, especially with high-dose magnesium, potassium, or calcium Red blood cell problems in people with G6PD deficiency, a genetic enzyme issue

The use of P5091 or P22077, two USP7 inhibitors, display a strong senolytic activity in several models of senescence 31

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Combined therapy of silymarin and desferrioxamine in patients with beta-thalassemia major: a randomized double-blind clinical trial