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While this effect appears to be related to the magnitude and rapidity of glucose lowering rather than a direct effect of the medication itself, patients with a history of diabetic retinopathy should undergo careful ophthalmologic evaluation before and during treatment, and the potential risks should be weighed against the expected benefits of improved glycemic control

J Biol Chem 277:2694426949

Total client assets hit $2.509 trillion on December 31, 2025. Total Loss Absorbing Capacity ratio was 23.22% of risk-weighted assets in 2025. Allowance for credit losses on loans was $14.3 billion as of December 31, 2025

doi:10.1001/jamainternmed.2018.3034 Das L et al (2018): Unmasking and aggravation of polycythemia vera by canagliflozin

The obtained frequency spectrum for each subject is shown in Fig
