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Vitamin B12 is water-soluble meaning your body uses what it needs and naturally eliminates the rest

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(HEALTHLINE: Losing weight on GLP-1 drugs like Ozempic, Wegovy, Mounjaro, and Zepbound may increase your risk of developing nutrient deficiencies) Tirzepatide has a dual approach with both GLP and GIP benefits

1996 Nov;15(5):456-64

However, researchers emphasized that larger and more comprehensive studies are still needed before definitive conclusions can be made