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Clinical administration uses pharmaceutical-grade compounds with documented purity certificates and proper cold-chain handling

they add to carbonyl carbons instead (1,2-addition), as do organolithium reagents and LiAlH 4

doi: 10.3390/CELLS9122660 16

[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Moraes R.C.M., Singulani M.P., Gonalves A.C., Portari G.V., Torro A.D.S

Further research is needed to fully elucidate the underlying mechanisms, as the cumulative body of evidence supports the potential of probiotics for both the prevention and management of human diseases associated with gut microbiome dysregulation