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The bioavailability of LA is approximately 30% (2038%), primarily due to the first-pass effect in the liver [18]

MOTS-c's observed capacity to influence fat metabolism and insulin sensitivity highlights its significance in the context of metabolic dysfunction research and offers novel insights into further investigation of obesity and diabetes

Biochem Soc Trans 18(6):10541056

doi: 10.1016/j.transproceed.2007.06.001