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Autophagy dysregulation in amyotrophic lateral sclerosis
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doi: 10.3389/fsufs.2022.1030540 116 LiuR.LalR
However, the melatonin synthesized by extrapineal organs could not replace the function of melatonin produced by pineal gland, such as the regulation of circadian rhythms [49], the neuroprotection, and anti-inflammatory responses [50, 51]
Why most acute stroke studies are positive in animals but not in patients: a systematic comparison of preclinical, early phase, and phase 3 clinical trials of neuroprotective agents
