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doi: 10.1007/s11051-023-05668-8 [DOI] [Google Scholar] 63.Kurano T, Kanazawa T, Ooba A, et al

To signal, FGFs are released from the extracellular matrix by heparinases, proteases or specific FGF binding proteins, and the liberated FGFs subsequently bind to cell surface heparan sulphate proteoglycans (HPSGs) stabilizing the FGF-FGFR interaction [135]