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Pharmacokinetics (PK) and pharmacodynamics (PD) of RG7112, an oral murine double minute 2 (MDM2) antagonist, in patients with leukemia and solid tumor

Dosw 70 , 4831498

Site-specific identification: Acquire diagnostic fragments to easily identify the site of metabolism for glucuronide metabolites with EAD
These CCR4+ Tregs are subsequently attracted to the tumor tissue by CCL22 and CCL17 secreted within the TME (Sarkar et al., 2022)
doi: 10.48208/HeadacheMed.2023.35
