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Lipid metabolic reprogramming in tumor microenvironment: from mechanisms to therapeutics

Recent studies have shown that constitutively active LXR in macrophages can stimulate cholesterol efflux and inhibit inflammation triggered by lipopolysaccharide (LPS) [125]

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We discuss literature data demonstrating that ROS are generated in endometriotic tissues that have physical proximity to gametes and embryos, and demonstrating adverse impacts on oocyte, sperm and embryo microtubule apparatus, chromosomes, and DNA