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A prior study identified six putative phosphorylation sites (S155, T189, T216, S246, S284, T292) within ArfGAP1 by mass spectrometry yet no quantitative analysis was provided, and it was unclear which LRRK2 variants were used in these assays, including whether comparison to a kinase-inactive LRRK2 negative control was included (Xiong et al., 2012)

Different types of mechanisms might be involved in the development of stroke in cannabis users including orthostatic hypotension with the secondary impairment of the CBF autoregulation, altered cerebral vasomotor function, supine hypertension, and fluctuations in blood pressure, cardioembolism with atrial fibrillation, vasculopathy and vasospasm (Wolff et al., 2013

Prog Neurobiol 13:277323 Bak LK, Schousboe A, Waagepetersen HS (2006) The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer

In the track events, there were three false starts, each of which typically means an automatic disqualification for the violator

Enantiomers were separated and according to computational modeling the inhibitory capacity of the compounds were attributed to the S -configuration of the spiro-oxindole dihydroquinazolinones