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[DOI] [PMC free article] [PubMed] [Google Scholar] 315.Wilson WW, Wade MM, Holman SC, and Champlin FR

Hays, R

Lipophagy prevents activity-dependent neurodegeneration due to dihydroceramide accumulation in vivo

Brain iron accumulation Cerebral iron accumulation, a prevalent comorbidity in a multitude of cognitive and motor function disorders such as AD, PD, multiple system atrophy, and multiple sclerosis, is often evidenced by heightened iron deposition in the brain [469, 503, 798803]

Oxidative stress plays an essential and complex role throughout its occurrence and progression [26], to which reactive oxygen species (ROS) are the primary contributors