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The downregulation of macrophages activity through the overexpression of CD47 is already known as a mechanism for cancer cells to escape the immune system

Most interestingly, this is very important for B cells, while in our previous studies we could restore functionality of Gclc- deficient T cells by ROS-scavenging with N-acetyl cysteine and GSH 43,44

In healthy intestinal function, these cells take up antigens from the intestine to determine immune tolerance (not harmful) or immune response (harmful)

[DOI] [PubMed] [Google Scholar] 9.Schiller HJ, Reilly PM, Bulkley GB
