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Liposome/gold hybrid nanoparticle encoded with CoQ10 (LGNP-CoQ10) suppressed rheumatoid arthritis via STAT3/Th17 targeting

In the past century, the average temperature has risen more than 2 degrees F, with a notable increase in the number of extremely hot days and warm nights

Systematically decipher the functional mechanisms of non-canonical defense pathways (FSP1-coenzyme Q10, GCH1-BH4, and DHODH) in periodontal tissues (129131), validate their regulatory roles through gain-of-function and loss-of-function experiments, and develop targeted agonists or lipid droplet-directed nanomedicines for therapeutic intervention (132134)

Microglia-specific metabolic changes in neurodegeneration

Peptide therapy offers an alternative approach, focusing on promoting the bodys natural regenerative capabilities without the need for invasive procedures