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It has been shown to significantly reduce visceral adipose tissue (VAT) in multiple randomized trials (NEJM/phase III evidence

Symptoms of B12 deficiency include: Fatigue Low mood or personality/mood changes Irritability Lethargy Headaches Palpitations Loss of appetite Pale yellow tint to the skin A feeling of pins and needles (paraesthesia) Poor memory Impaired cognitive performance Depression Weakness Impaired digestion Inflammation Gastrointestinal lesions Neurological damage Since B12 is primarily found in animal products, any change in ones diet that leads to a decrease in the consumption of such products such as a vegan , vegetarian, or low-fat diet can increase the chance of a person developing a B12 deficiency

Is it safe long-term

The titration protocol (starting at 2 mg and increasing every four weeks) is essential for tolerability

Stengler: So how can vitamin B12 shots help you