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If the patient has a macroadenoma and a serum prolactin level of less than 200 ng/mL (4000mU/L), consideration should be given to the possibility that a nonfunctioning pituitary adenoma is present, and the hyperprolactinemia is a result from the deprivation of some lactotrophs of dopaminergic inhibition (3)

It is not a substitute for personalized medical advice

Dhalluin, C

For instance, tumours with high endogenous CCNE1 expression, which encodes the oncogene cyclin E1, are HR proficient and inherently resistant to DNA-damaging agents 6