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Some companies may even feel they are not competent to pursue brain targets where the BBB is a challenge

In contrast, the Cys-targeted redox proteomics approach allows us to identify oxidized proteins/enzymes and further predict their functional alterations (e.g., inhibition) even in the absence of any changes in protein contents by simply searching the literature

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Detection of condensin domain disruption caused by cnd1-K658E mutation using FISH microscopy Since Hi-C analysis indicated that condensin domains were impaired in the cnd1-K658E mutant, we sought to examine domain organization in the mutant using a FISH-based microscopic approach

Trends Genet 23:413418 Robertson KD (2005) DNA methylation and human disease
