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It works through multiple mechanisms, increasing blood vessel formation around follicles, reducing inflammation, stimulating collagen synthesis in the dermal papilla, and blocking 5-alpha reductase, the enzyme that converts testosterone to the follicle-damaging DHT

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After we estimate the model, we assign comorbidities to the low comorbidity adjustment if any comorbidities have a coefficient that is statistically significant (p-value of 0.05 or less) and which have a coefficient that is larger than the 50th percentile of positive and statistically significant comorbidity coefficients

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