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Enzyme-responsive type In contrast to enzyme-responsive drug carriers (see above) where enzymatic cleavage releases small-molecule drugs from carrier matrices, the approaches in this subsection employ enzymatic reactions to directly destabilize the lysosomal membrane, facilitating escape of the carrier and its macromolecular cargo

Associations of plasma aflatoxin B1-albumin adduct level with plasma selenium level and genetic polymorphisms of glutathione S-transferase M1 and T1

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Vega et al., 1998), as well as subsequent disruption of the active GSTP1-1 dimer (Jenkins et al., 2008)