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S100A7 can also be produced by circulating cells, possibly contributing to systemic inflammation and psoriasis-associated comorbidities ( S100A7 exerts many functions, depending on its interaction with specific target proteins

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126 In a randomized controlled trial, 40 patients with tinnitus (17 of whom also had vitamin B12 deficiency with levels below 250 pg/mL) were treated with weekly intramuscular injections providing 2,500 mcg vitamin B12 or saline (placebo) for six weeks
