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Increased Plasma PCSK9 Levels Are Associated with Reduced Endotoxin Clearance and the Development of Acute Organ Failures during Sepsis

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In mice, THC exposure from embryonic day 12.5 to embryonic day 16.5, a critical window for corticospinal motor neuron development, results in a transient decrease in CB1 content and binding in whole embryonic brain that is rescued by postnatal day 2