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The hypothesis of oxidative stress highlights the crucial role of antioxidant defenses as an important component of the overall redox balance of the organism

Murota, K., Nakamura, Y

The plant glutathione peroxidase enzymes (GPXs) may be involved in the detoxification of H 2 O 2 and organic hydroperoxides and in the regulation of the cellular redox homeostasis by maintaining the thiol/disulfide balance
After being stimulated with phorbol myristate acetate and ionomycin, CD4 + cells from individuals with LC produced significantly higher median levels of intracellular IL-2 (17% (LC), 14% (CC) and 13% (HC)) and IL-4 (11% (LC), 7% (CC) and 8% (HC)) (Extended Data Figs
