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Direct evidence of DJ-1s role in neuronal survival against ferroptosis comes from studies showing that dopaminergic neurons differentiated from induced pluripotent stem cells of PARK7 mutant carriers exhibit increased sensitivity to ferroptosis (93)

The graphs were made using GraphPad Prism 9 software (San Diego, CA, USA)

Glutathione functions as a redox-active biomolecule, primarily through its capacity to neutralize reactive molecular species such as free radicals and reactive oxygen species (ROS)