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Also, it is documented that in neurodegenerative diseases regional hypometabolism, oxidative stress, and altered metabolism of fatty acids and glucose occur

R., Zhou, H

Although the mechanism of ACO1 and transferrin affecting adipose tissue metabolism is unclear, ACO1 gene expression is significantly related to gene expression of proliferator-activated receptor-gamma coactivator 1-beta (PGC-1), which is critical to the mitochondrial function of adipose tissue [49]

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By comparison, the polyphenols which are large bulky higher molecular weight molecular structures typically exhibit bioavailability of around 1-8% [90]
