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In same study, treatment with potent inhibitor of PKR 2-aminopurine resulted in the reduction of apoptotic population by more than 50%

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Biogerontology 2016;17, 305-315, doi:10.1007/s10522-015-9610-z

348 While SERMs regulate ER activity instead of inhibiting it, promising results have been observed with lasofoxifene, a new-generation non-steroidal SERMs