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Clinical significance of combined circulating TERT promoter mutations and miR-122 expression for screening HBV-related hepatocellular carcinoma

JCI Insight 6 , e147789 (2021)
The TFCC makes it possible for the wrist to move in six different directions: bending, straightening, twisting both ways, and side-to-side
This pathway is hyperactivated in NF1-related tumours, and inhibition of MAPK kinase (MEK) was effective at controlling tumour size in a mouse model of NF1
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