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Beyond the molecule's own profile, real-world risks cluster around administration and product quality
Proc Natl Acad Sci USA 110:95359540 Colloby SJ, McParland S, OBrien JT, Attems J (2012) Neuropathological correlates of dopaminergic imaging in Alzheimers disease and Lewy body dementias
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They found that early activation of Nrf2 by oxidative stress up-regulated xCT expression and cystine uptake, leading to increased formation of persulfide metabolites, which terminated IL-1 production
afranko, S., et al
