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Efficacy of pregabalin as a monotherapy versus combined pregabalin and milnacipran in the management of fibromyalgia

doi: 10.1016/j.ejphar.2004.12.018

In addition, increased BBB permeability to macromolecules has recently been shown to be linked to suppression of transcytosis by vitronectin, an ECM protein secreted by pericytes, which acts by binding to the 5-integrin receptor expressed on endothelial cells (Ayloo et al, 2022)

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Whether used alone or with compounded semaglutide or compound tirzepatide, this peptide promises to be a central figure in the future of obesity management and research