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Connexins also exert numerous nonchannel functions: they regulate astrocyte morphology and interactions with synapses, influence gene expression, control glial reactivity and modulate mitochondrial function and ATP production 475,476,477
conducted an observational study on 92 HCC patients, demonstrating that the methylation levels of the VTRNA2-1 promoter were higher in tumor tissues than adjacent normal tissues and significantly correlated with unfavorable clinical outcomes in HCC patients [284]
Yang et al., 2024[159]
We are so truly grateful to Alberto Ospite and Diego Discepoli, as well as to Laura Buonfino, Stefano Marzeglia, and Marco Pasinetti, for the organization of various overwhelmingly successful fundraising events in London in support of our research as well as to all the donors contributing to these initiatives, as documented at the sites: or /genome21research
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