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10.1053/j.jfas.2011.05.002 43 NajafbeygiA.FatemiM

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Tight connections created by endothelial cells provide not just a physical barrier, but also constitute a molecular barrier that tightly restricts substance movement
Moreover, in addition to respiratory supplementation of oxygen, treatments that target the oxidative metabolism of tumor cells have received much attention recently, which could be another efficacious way to decrease intratumoral hypoxia and relieve the immunosuppression of the TME
Thomas, F.C
