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Apart from these clear differences, each form of regulated necrosis is defined by a 3-step cell death process including initiating, propagating and executioning steps resulting in plasma membrane permeabilization [42] in which the dysregulation of the cellular redox metabolome acts as a common denominator

doi: 10.1136/jcp.2006.038976 [DOI] [PMC free article] [PubMed] [Google Scholar] 115
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Precise and efficient silencing of mutant Kras(G12D) by CRISPR-CasRx controls pancreatic cancer progression
