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Two major populations of circulating monocytes exist in mice: lymphocyte antigen 6C + (Ly6C + ) high (Ly6C hi )-expressing monocytes are present in the bone marrow, and Ly6C low (Ly6C lo )-expressing monocytes are derived from the spleen ( + F4/80 + macrophages originate from infiltrating monocytes, while CD11b lo F4/80 hi macrophages are derived from resident KCs and mature monocytes ( The monocytes in mice are marked with Ly6C hi and CC-chemokine receptor 2 hi (CCR2 hi ) ( hi monocytes in early murine steatohepatitis are mainly identified by chemokine receptors, pattern recognition receptors (PRRs), and cytokine secretion ( lo monocytes are characterized by their scavenger receptors ( Another liver-resident macrophage subset is the LCM

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Branch-specific dendritic Ca(2+) spikes cause persistent synaptic plasticity

doi: 10.3390/cancers11091255 95 MaLYangFWuXMaoCGuoLMiaoTet al
a summary of clinical and experimental observations
