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10.3390/ijerph14101139 65 TanW

Unlike the transketolase used in the last reaction, the transaldolase enzyme does NOT use TPP as a cofactor

Clinical signs encompass bone spicule-shaped pigment deposits, retinal atrophy, attenuation of retinal vessels, and a pale appearance of the optic nerve head [343]

For example: Via a transketolase reaction, xyulose 5-phosphate, which is simply an epimer of ribulose 5-phosphate , (a 5-carbon molecule) reacts with ribose 5-phosphate (another 5-carbon molecule) to form glyceraldehyde 3-phosphate (a 3-carbon molecule) and sedoheptulose 7-phosphate (a 7-carbon molecule)

It binds to toxins and helps to neutralize them, making it easier for the body to eliminate these harmful substances